Take a look at our projects

Common microbes (viruses, bacteria and fungi) may play a significant role in neurodegeneration! Using multiple tools we possess and invent, we investigate the Pathogen Hypothesis, namely the role of microbes in contributing to Alzheimer’s disease, Parkinson’s disease, CTE and ALS.

Many diseases of the nervous system are characterized by altered physiology. We create tools that investigate how brain activity changes at subcellular resolution, so we can understand how pathological molecular events reshape the entire network activity, and lead to cognitive decline.

Inorganic nanoparticles hold great promise to monitor and reverse pathology, since they are able to withstand physical conditions that proteins and nucleic acids cannot. However, getting them to the right place at the right time is very challenging. We are engineering nanoparticles to be controlled by their target cells.

We create technologies that enable genetic access to specific cell types in the brain (no viruses!).

How do we know that a biological phenomenon is detrimental to the brain? Simply put, we gain control over it. We create optogenetic tools that actuate or report aspects of brain disease and we turn them on and off, one at a time. 

Every brain disease has its own characteristic pathology. By creating molecular and optical technologies that read out different aspects and stages of diseases, we are able to image the pathological cascade of events in real time in the live brain.

We build molecular technologies to enable vision restoration in the blind. We work to help restoration of sight through novel technologies and techniques. Our aim is to increase the quality of life for those challenged by loss of vision.